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ISLET AMYLOID POLYPEPTIDE
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DeCS
Descriptor
English
:
Islet Amyloid Polypeptide
Descriptor
Spanish
:
Polipéptido Amiloide de los Islotes Pancreáticos
Descriptor
Portuguese
:
Polipeptídeo Amiloide das Ilhotas Pancreáticas
Tree Number:
D12.644.548.586.234
D12.776.049.407.500
Definition
English
:
A pancreatic beta-cell hormone that is co-secreted with
INSULIN
. It displays an anorectic effect on nutrient
metabolism
by inhibiting
gastric acid
secretion,
gastric emptying
and postprandial
GLUCAGON
secretion.
Islet amyloid polypeptide
can fold into
AMYLOID
FIBRILS that have been found as a major constituent of pancreatic
AMYLOID
DEPOSITS.
Pharmacological Action:
Appetite Depressants
History Note
English
:
2011
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
54057
Unique Identifier:
D058228
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS